Mm00023212_cn

• Gene Symbol: Bmpr2
• Assay Reference Genome Location: Chr.1:59852329 on build GRCm38
• Cytoband: 1C2

Target Gene Details

• Entrez Gene ID: 12168
• Gene Name: bone morphogenetic protein receptor, type II (serine/threonine kinase)
• Gene Aliases: 2610024H22Rik, AL117858, AW546137, BB189135, BMP-2, BMPR-2, BMPR-II, BMPRII, BRK-3, Gm20272
• Location: Chr.1:59764270-59878081 on Build GRCm38
• Assay Gene Location: Overlaps Intron 8 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Bmpr2	NM_007561.4			NP_031587.1
	AF003942.1			AAB63042.1
	AK148180.1			BAE28400.1
	U78048.1			AAB87638.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

mesoderm formation
maternal placenta development
positive regulation of protein phosphorylation
endothelial cell proliferation
positive regulation of endothelial cell proliferation
lymphangiogenesis
blood vessel remodeling
chondrocyte development
negative regulation of systemic arterial blood pressure
transcription from RNA polymerase II promoter
protein phosphorylation
transmembrane receptor protein serine/threonine kinase signaling pathway
anterior/posterior pattern specification
positive regulation of endothelial cell migration
positive regulation of epithelial cell migration
positive regulation of pathway-restricted SMAD protein phosphorylation
regulation of lung blood pressure
phosphorylation
negative regulation of cell growth
positive regulation of bone mineralization
BMP signaling pathway
positive regulation of BMP signaling pathway
regulation of cell proliferation
positive regulation of osteoblast differentiation
negative regulation of vasoconstriction
vascular endothelial growth factor receptor signaling pathway
lung alveolus development
positive regulation of axon extension involved in axon guidance
limb development
lymphatic endothelial cell differentiation
artery development
venous blood vessel development
retina vasculature development in camera-type eye
endothelial cell apoptotic process
negative regulation of chondrocyte proliferation
negative regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor binding
BMP binding
metal ion binding