Mm00060981_cn

• Gene Symbol: Itch
• Assay Reference Genome Location: Chr.2:155218042 on build GRCm38
• Cytoband: 2H1

Target Gene Details

• Entrez Gene ID: 16396
• Gene Name: itchy, E3 ubiquitin protein ligase
• Gene Aliases: 6720481N21Rik, 8030492O04Rik, A130065M08, AIP4, C230047C07Rik
• Location: Chr.2:155133379-155226855 on Build GRCm38
• Assay Gene Location: Within Exon 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Itch	NM_001243712.1	24	2782	NP_001230641.1
	NM_008395.3	23	2580	NP_032421.2
	AF037454.1	23	2496	AAB99764.1
	AK220164.1	24	2704	BAD90349.1
	BC062934.1	23	2529	AAH62934.1
	BC064678.1			AAH64678.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
immune system process
positive regulation of T cell anergy
ubiquitin-dependent protein catabolic process
apoptotic process
protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
protein K29-linked ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
innate immune response
positive regulation of protein catabolic process
negative regulation of JNK cascade
negative regulation of alpha-beta T cell proliferation
negative regulation of defense response to virus
defense response to virus
protein K63-linked ubiquitination
protein K48-linked ubiquitination
regulation of protein deubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
ribonucleoprotein complex binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
CXCR chemokine receptor binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity