Mm00313624_cn

• Gene Symbol: Map3k5
• Assay Reference Genome Location: Chr.10:20059016 on build GRCm38
• Cytoband: 10A3

Target Gene Details

• Entrez Gene ID: 26408
• Gene Name: mitogen-activated protein kinase kinase kinase 5
• Gene Aliases: 7420452D20Rik, ASK, ASK1, MAPKKK5, Mekk5
• Location: Chr.10:19934513-20142750 on Build GRCm38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Map3k5	NM_008580.4	10	1707	NP_032606.4
	AB006787.3	10	1759	BAA23648.3
	BC116627.1	10	1707
	BC116628.1	9	1683
	BC133697.1	10	1707

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
activation of MAPK activity
positive regulation of protein phosphorylation
immune system process
protein phosphorylation
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
JNK cascade
intrinsic apoptotic signaling pathway in response to oxidative stress
regulation of cell death
phosphorylation
response to endoplasmic reticulum stress
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of JUN kinase activity
innate immune response
positive regulation of JNK cascade
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to hydrogen peroxide
programmed necrotic cell death
positive regulation of neuron death
cellular response to reactive nitrogen species

Function(s)

nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein phosphatase binding
protein homodimerization activity
metal ion binding