Mm00328006_cn

• Gene Symbol: Alox15
• Assay Reference Genome Location: Chr.11:70345549 on build GRCm38
• Cytoband: 11B3

Target Gene Details

• Entrez Gene ID: 11687
• Gene Name: arachidonate 15-lipoxygenase
• Gene Aliases: 12-LO, 12/15-LO, 15-LOX, Alox12l, L-12LO
• Location: Chr.11:70344147-70375918 on Build GRCm38
• Assay Gene Location: Overlaps Intron 11 - Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Alox15	NM_009660.3			NP_033790.3
	AK142371.1			BAE25045.1
	BC056625.1			AAH56625.1
	BC081546.1			AAH81546.1
	CT010263.1			CAJ18471.1
	L34570.1			AAA64930.1
	U04331.1			AAA20658.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

ossification
negative regulation of adaptive immune response
lipid metabolic process
fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
bone mineralization
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
apoptotic cell clearance
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
phosphatidylinositol-4,5-bisphosphate binding
lipid binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity
dioxygenase activity