Mm00397576_cn

• Gene Symbol: Clu
• Assay Reference Genome Location: Chr.14:65968536 on build GRCm38
• Cytoband: 14D1

Target Gene Details

• Entrez Gene ID: 12759
• Gene Name: clusterin
• Gene Aliases: AI893575, ApoJ, Cli, D14Ucla3, SP-40, Sgp-2, Sgp2, Sugp-2
• Location: Chr.14:65968483-65981547 on Build GRCm38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Clu	NM_013492.2	1	54	NP_038520.2
	BY248781.1	1	54

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

cell morphogenesis
microglial cell activation
cell death
positive regulation of cell proliferation
protein import
endocrine pancreas development
central nervous system myelin maintenance
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of protein homooligomerization
positive regulation of tumor necrosis factor production
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
neuron projection morphogenesis
protein stabilization
positive regulation of NF-kappaB transcription factor activity
chaperone-mediated protein complex assembly
response to misfolded protein
chaperone-mediated protein folding
microglial cell proliferation
intrinsic apoptotic signaling pathway
regulation of beta-amyloid clearance
regulation of neuron death
positive regulation of neuron death
positive regulation of beta-amyloid formation
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of beta-amyloid formation
regulation of neuronal signal transduction
positive regulation of tau-protein kinase activity
positive regulation of neurofibrillary tangle assembly
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
ubiquitin protein ligase binding
protein N-terminus binding
misfolded protein binding