Mm00473354_cn

• Gene Symbol: Pdpk1
• Assay Reference Genome Location: Chr.17:24091543 on build GRCm38
• Cytoband: 17A3.3

Target Gene Details

• Entrez Gene ID: 18607
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: Pdk1
• Location: Chr.17:24073680-24150922 on Build GRCm38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Pdpk1	NM_001080773.2	10	1146	NP_001074242.1
	NM_001286662.1	10	1064	NP_001273591.1
	NM_011062.4	10	1146	NP_035192.2
	AF079535.1	10	1103	AAC96115.1
	AF086625.1	10	1112	AAC67544.1
	AF126294.1	10	1087	AAD38505.1
	AK147149.1	10	1138	BAE27716.1
	AK147835.1	10	1121	BAE28171.1
	AK149162.1	10	1080
	AK149289.1	10	1104	BAE28793.1
	AK162677.1	10	1106	BAE37017.1
	AK165564.1	10	1083
	AK188106.1	2	114
	AK193731.1	2	79
	AK205439.1	1	59
	AK219503.1	2	72
	AY062008.1	10	1042	AAL47185.1
	BC146001.1	10	1083
	BC146003.1	10	1083

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
phosphorylation
cell migration
peptidyl-threonine phosphorylation
calcium-mediated signaling
negative regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
focal adhesion assembly
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
phospholipase binding