Mm00516161_cn

• Gene Symbol: G6pdx
• Assay Reference Genome Location: Chr.X:74411264 on build GRCm38
• Cytoband: XA7.3

Target Gene Details

• Entrez Gene ID: 14381
• Gene Name: glucose-6-phosphate dehydrogenase X-linked
• Gene Aliases: G28A, G6pd, Gpdx
• Location: Chr.X:74409486-74429161 on Build GRCm38
• Assay Gene Location: Overlaps Intron 9 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
G6pdx	NM_008062.2			NP_032088.1
	AK088135.1			BAC40166.1
	AK148031.1
	AK165207.1			BAE38077.1
	BC075663.1			AAH75663.1
	Z11911.1			CAA77967.1

Target Gene Details

• Entrez Gene ID: 16151
• Gene Name: inhibitor of kappaB kinase gamma
• Gene Aliases: 1110037D23Rik, AI848108, AI851264, AW124339, IKK[g], NEMO
• Location: Chr.X:74393291-74456792 on Build GRCm38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ikbkg	NM_001161423.1			NP_001154895.1
	NM_001161424.1			NP_001154896.1
	CJ099503.1
	CN717929.1
	CV556906.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic

Panther Classification:

Molecular Function -

dehydrogenase

Gene Ontology Categories:

Process(es)

cytokine production
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
carbohydrate metabolic process
glucose metabolic process
pentose-phosphate shunt
cholesterol biosynthetic process
NADP metabolic process
NADPH regeneration
NADP biosynthetic process
glutathione metabolic process
response to oxidative stress
pentose-phosphate shunt, oxidative branch
negative regulation of protein glutathionylation
pentose biosynthetic process
interleukin-10 production
interleukin-12 production
cellular response to oxidative stress
regulation of multicellular organism growth
erythrocyte maturation
regulation of neuron apoptotic process
response to ethanol
ribose phosphate biosynthetic process
erythrocyte development
glucose 6-phosphate metabolic process
oxidation-reduction process
B cell homeostasis
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
activation of NF-kappaB-inducing kinase activity
positive regulation of gene expression
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
positive regulation of NF-kappaB transcription factor activity
establishment of vesicle localization
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

glucose-6-phosphate dehydrogenase activity
glucose binding
oxidoreductase activity
carbohydrate binding
identical protein binding
protein homodimerization activity
NADP binding
protein binding
protein domain specific binding
ubiquitin protein ligase binding
peroxisome proliferator activated receptor binding
metal ion binding
protein heterodimerization activity
K63-linked polyubiquitin binding
linear polyubiquitin binding