Mm00607574_cn

• Gene Symbol: Map3k1
• Assay Reference Genome Location: Chr.13:111755320 on build GRCm38
• Cytoband: 13D2.2

Target Gene Details

• Entrez Gene ID: 26401
• Gene Name: mitogen-activated protein kinase kinase kinase 1
• Gene Aliases: MAPKKK1, MEKK1, Mekk
• Location: Chr.13:111746433-111818269 on Build GRCm38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Map3k1	NM_011945.2	14	3414	NP_036075.2
	AF117340.1	14	3414	AAD25049.1
	L13103.1	4	1423	AAA97500.1
	U23470.1	1	1015	AAA85038.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
epithelial cell morphogenesis
protein phosphorylation
transforming growth factor beta receptor signaling pathway
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
regulation of mitotic cell cycle
apoptotic mitochondrial changes
phosphorylation
protein ubiquitination
regulation of cell migration
positive regulation of actin filament polymerization
wound healing
regulation of apoptotic process
camera-type eye development
eyelid development in camera-type eye

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
MAP kinase kinase kinase activity
ubiquitin-protein transferase activity
protein binding
ATP binding
zinc ion binding
JUN kinase binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
mitogen-activated protein kinase kinase binding
sphingolipid binding
metal ion binding
mitogen-activated protein kinase binding