Mm00625376_cn

• Gene Symbol: Tap2
• Assay Reference Genome Location: Chr.17:34216185 on build GRCm38
• Cytoband: 17B1

Target Gene Details

• Entrez Gene ID: 21355
• Gene Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
• Gene Aliases: ABC18, AI462429, APT2, Abcb3, Ham-2, Ham2, MTP2, PSF2, RING11, Tap-2, Y1, jas
• Location: Chr.17:34204085-34216321 on Build GRCm38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Tap2	NM_011530.3	12	2354	NP_035660.3
	AK020022.1	11	2430
	AK079667.1	12	2268
	AK145234.1	12	2313
	AK151376.1	12	2264	BAE30348.1
	AK151483.1	12	2264	BAE30436.1
	AK151657.1	12	2287
	AK153287.1	12	2264	BAE31870.1
	AK159200.1	12	2320	BAE34894.1
	AK161091.1	12	2270
	AK169645.1	9	1562
	BC005578.1	12	2254	AAH05578.1
	BC051257.1	12	2267	AAH51257.2
	BE691532.1	1	137
	U60087.1			AAB41970.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
response to molecule of bacterial origin
immune system process
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
positive regulation of antigen processing and presentation of peptide antigen via MHC class I
protein complex assembly
transport
protein transport
peptide transport
intracellular transport of viral protein in host cell
antigen processing and presentation of endogenous peptide antigen via MHC class I
protection from natural killer cell mediated cytotoxicity
cytosol to ER transport
peptide antigen transport
transmembrane transport

Function(s)

nucleotide binding
protein binding
ATP binding
peptide transporter activity
peptide antigen-transporting ATPase activity
peptide-transporting ATPase activity
ATPase activity
MHC class Ib protein binding
MHC protein binding
MHC class I protein binding
peptide antigen binding
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
ADP binding
TAP1 binding
TAP2 binding
tapasin binding
protein heterodimerization activity