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Medchemexpress LLC 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione | 1208222-39-2 | MFCD22683818 | 99.4% | 397.35 g·mol^-1 | C22H14F3NO3 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY10765110MG

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VU 0365114 is a selective muscarinic acetylcholine receptor (mAChR) M5 positive allosteric modulator used in research to potentiate M5-mediated signaling. It displays an EC50 of 2.7 μM for M5 with minimal activity at M1-M4 and has been reported to increase acetylcholine-stimulated insulin secretion in human β-cells.

  • Selective mAChR M5 positive allosteric modulator.
  • Potentiates M5 responses with EC50 of 2.7 μM.
  • Minimal activity at M1-M4 receptors (EC50 > 30 μM).
  • High purity solid with light yellow to orange appearance.
  • Chemical formula C22H14F3NO3; molecular weight 397.35 g·mol⁻¹.
  • Intended for biochemical and pharmacological research applications.

Catalog No. 50-002-42026


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