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Medchemexpress LLC 1,1,1-Trifluoroethyl-PEG2-propargyl | 1835759-73-3 | ≥97.0% | C9H13F3O3 | 100 MG

Supplier: Medchemexpress LLC HY140886100MG
1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Azide groups. This design enables PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables selective degradation of target proteins via ubiquitin-proteasome system
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