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Medchemexpress LLC [1,1'-Biphenyl]-4-carboxamide, 5'-[(5-amino-6-chloro-4-pyrimidinyl)amino]-2'-fluoro-N,N-dimethyl-4' | 2378768-36-4 | C24H27ClFN7O | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY153331

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DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. It selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research.

  • Orally active and potent WDR5-MLL1 inhibitor
  • Has an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein
  • Selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity
  • Inhibits the proliferation of MLL translocation-harboring cells
  • Useful for MLL fusion leukemia research

Catalog No. 50-003-75419


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