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Medchemexpress LLC 1-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole | 2411969-39-4 | 99.3% | 282.05 | C9H4Cl2F3N3 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY14751910MG

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ARUK3001185 is a potent, selective Notum inhibitor developed for research into Wnt signaling and related biological pathways. It is orally active and brain-penetrant, with an IC50 of 6.7 nM, and has demonstrated in vivo exposure in plasma and brain after oral dosing. The compound is supplied as a high-purity solid suitable for biochemical assays and in vivo studies.

  • Potent, selective inhibitor of Notum (IC50 = 6.7 nM).
  • Orally active and brain-penetrant.
  • Restores Wnt signaling in vitro.
  • Demonstrated plasma and brain exposure in mouse studies after oral dosing.
  • High purity suitable for research use (≈99.3%).
  • Available in multiple solid quantities for dosing and screening.

Catalog No. 50-002-86075


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