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Medchemexpress LLC 1-(2,5-dioxopyrrolidin-1-yl)oxy-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid | 1193111-39-5 | MFCD20227457 | 92.1% | 406.45 | C13H14N2O7S3 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY10115125MG

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sulfo-SPDB is a cleavable antibody-drug conjugate (ADC) linker featuring a pyridyldisulfide-based disulfide that is reductively cleavable and a sulfonic acid moiety to improve solubility. It is supplied for research use and is designed for preparing linker-drug intermediates and conjugation to antibodies under controlled, reducing conditions.

  • Cleavable disulfide linker enabling reductive release of payload.
  • Sulfonic acid group improves aqueous solubility.
  • High solubility in DMSO (≥125 mg/mL) for formulation flexibility.
  • Compatible with standard ADC conjugation workflows.
  • Requires cold storage and protection from light for stability.

Catalog No. 50-002-12234


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