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Medchemexpress LLC 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-propylurea | 286370-15-8 | 99.5% | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1206010MG

Encompass_Preferred

KRN-633 is a small-molecule vascular endothelial growth factor receptor (VEGFR) inhibitor used in research to study angiogenesis and kinase signaling. It inhibits VEGFR1, VEGFR2, and VEGFR3 with reported IC50 values of 170, 160, and 125 nM, respectively, and has demonstrated activity against c-Kit and PDGFR-β in cellular assays and antitumor effects in xenograft models.

  • Inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50 = 170, 160, 125 nM).
  • Blocks VEGFR phosphorylation and VEGF-driven endothelial cell proliferation.
  • High purity (99.5%) and solid, white to off-white appearance.
  • Available in multiple quantities, including small-scale mg vials and ready-to-use DMSO solutions.
  • Recommended storage: powder at -20 °C or 4 °C; solutions at -80 °C or -20 °C.

Catalog No. 50-002-34422


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