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Cayman Chemical 1- 3-ChlorophenylbIgunIde 5g
SDP

Supplier:  Cayman Chemical 347265 G

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A 5-HT3 receptor agonist; selectively binds 5-HT3 over 5-HT1A and 5-HT2 receptors (Kis = 0.002, 10, and 10 µM, respectively) but also binds to high and low affinity sites on the dopamine transporter (DAT; IC50s = 0.4 and 34.8 µM, respectively, in rat caudate putamen synaptosomal membranes); induces depolarization of isolated rat vagus nerve and stimulates inositol phosphate formation in rat frontocingulate cortical slices (EC50s = 0.05 and 4.2 µM, respectively); induces bradycardia in anaesthetized cats (ED50 = 20.3 nmol/kg)

Catalog No. 50-291-0588


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