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Medchemexpress LLC 1-[4-(3-ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-(piperazinyl)urea | 1173204-81-3 | MFCD18251484 | 99.2% | 570.65 | C29H34N10O3 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1068350MG

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A selective, reversible, ATP-competitive small-molecule inhibitor of class I PI3K isoforms and mTOR, exhibiting low-nanomolar potency against PI3Kα (including H1047R and E545K mutants), PI3Kβ, PI3Kγ, PI3Kδ, and mTOR. Intended for research use in biochemical and cellular studies of PI3K/mTOR signaling.

  • Low-nanomolar potency (PI3Kα 2 nM; PI3Kβ 7 nM; PI3Kγ 16 nM; PI3Kδ 14 nM; mTOR 3 nM).
  • Active against clinically relevant PI3Kα mutants (H1047R, E545K).
  • Reversible, ATP-competitive mechanism suitable for kinase assays.
  • High purity (99.17%) for reliable experimental results.
  • Characterized molecular formula C29H34N10O3 and molecular weight 570.65.
  • Suitable for biochemical, cellular, and target-validation studies.

Catalog No. 50-002-40813


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