Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502983268

Cayman Chemical 1 4dIdeoxy1 4ImInoDArabI 10mg
SDP

Supplier:  Cayman Chemical 2093910 MG

Encompass_Preferred

An ALK inhibitor (IC50s 3 5 10 and 5 4 nM for the wild-type ALKF1174L and ALKR1275Q enzymes respectively) selective for ALK over a panel of 86 kinases at 1000 nM but also inhibits ROS1 and TNK2 (IC50s 8 9 and 5 8 nM respectively) inhibits the proliferation of Ba/F3 cells expressing NPM-ALK or ELM4-ALK fusion proteins (IC50s 84 and 56 nM respectively) as well as several crizotinib-resistant Ba/F3 cells expressing NPM-ALK or ELM4-ALK mutants induces tumor regression in an NCI H2228 NSCLC mouse xenograft model at 10 and 30 mg/kg

Catalog No. 50-298-3268


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.