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Medchemexpress LLC 1-((5-chloropyridin-3-yl)methyl)-8-(3-methylmorpholino)-2-(trifluoromethyl)-pyrimido[1,2-a]pyrimidinone | 1523406-39-4 | MFCD28411361 | 99.7% | 443.85 g·mol⁻1 | C19H21ClF3N5O2 | 10MM 1ML
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Supplier:  Medchemexpress LLC HY1248110MM 1ML

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SAR405 is a selective, ATP-competitive inhibitor of Vps34 (class III PI3K) commonly used to study autophagy and vesicular trafficking in cellular and biochemical assays. It demonstrates potent target engagement and is supplied in a concentrated format for laboratory use.

  • Selective Vps34 inhibition with subnanomolar potency.
  • Reported IC50 ≈ 1.2 nM and Kd ≈ 1.5 nM.
  • High purity suitable for biochemical and cell-based assays.
  • Supplied as a concentrated solution for straightforward dosing.
  • Suitable for autophagy and PI3K class III pathway research.

Catalog No. 50-002-36499


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