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Medchemexpress LLC 1,5-Isoquinolinediamine, 6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-N1-[3-(trifluorometho... | 2274819-46-2 | 97.1% | 528.49 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11194050MG

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LUT014 is a topical BRAF inhibitor designed to address radiation-induced skin damage. It acts by inhibiting BRAF kinase and regulating the MAPK/ERK signaling pathway, promoting the repair and regeneration of damaged skin cells without passing the blood-brain barrier. It is particularly studied for treating radiation dermatitis, especially in breast cancer radiotherapy.

  • Topical BRAF inhibitor.
  • Inhibits BRAF kinase and activates MAPK/ERK signaling.
  • Promotes proliferation of epidermal keratinocytes.
  • Repairs skin barrier damage caused by radiation.
  • Alleviates inflammatory responses.
  • Independent of RAS signaling.
  • Accelerates repair and regeneration of damaged skin cells.
  • Suitable for studying radiation dermatitis.
  • Light yellow to yellow solid appearance.
  • Storage at 4°C, protected from light.
  • In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.

Catalog No. 50-004-39499


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