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Medchemexpress LLC 1-cyano-2-(2-methylbutan-2-yl)-3-(3-pyridinyl)guanidine | 60559-98-0 | 99.5% | 231.30 | 10 MG

Supplier: Medchemexpress LLC HY10857350MG
P-1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6), with an EC50 value of 45 nM for SUR2B-KIR6 channel activation. P-1075 also opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.
- Potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6).
- EC50 value of 45 nM for SUR2B-KIR6 channel activation.
- Opens mitochondrial K(ATP) channels.
- Generates reactive oxygen species.
- Results in cardioprotection of rabbit hearts.
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