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Medchemexpress LLC 1-Monopalmitin | 542-44-9 | 99.9% | 330.51 | 250 MG
Supplier: Medchemexpress LLC 250MGHYW009141
1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). It can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. It can also increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. This compound has the ability to induce protective autophagy and apoptosis of lung cancer cells, with low toxicity to normal cells.
- Induces G2/M arrest and caspase-dependent apoptosis in cancer cells.
- Inhibits IAPs protein expression.
- Increases drug accumulation by inhibiting P-gp activity.
- Induces protective autophagy and apoptosis of lung cancer cells.
- Exhibits low toxicity to normal cells.
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