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Cayman Chemical 1-NA-PP1, 221243-82-9, 5 mg
Supplier: Cayman Chemical 109545
Molecular Formula C19H19N5, Purity ≥98%, Formula Weight 317.4, Synonyms: 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 1-Naphthyl-PP1, PP1 Analog; A reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase; inhibits v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 M, respectively); used to elucidate functions of several kinases in both mammalian and yeast systems.
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