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Apexbio Technology LLC 1-Oleoyl lysophosphatidic acid sodium salt 325465-93-8 50mg
Supplier: Apexbio Technology LLC B751550
1-Oleoyl lysophosphatidic acid sodium salt (CAS 325465-93-8) is a naturally occurring lysophospholipid widely distributed in tissues It exerts diverse biological effects by binding to specific G protein-coupled lysophosphatidic acid (LPA) receptors including LPA1 and LPA3 In vitro it promotes tumor cell proliferation migration adhesion and inhibits apoptosis via receptor-mediated signaling while also upregulating VEGF and stimulating secretion of matrix metalloproteinases and angiogenic factors In vivo studies highlight its role in vascular remodeling particularly in hypoxic pulmonary hypertension and cellular chemotaxis Elevated plasma LPA levels serve as a potential biomarker for pancreatic cancer
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