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Cayman Chemical 10oxo12 ZOctadecenoIc AcI

Supplier: Cayman Chemical 36977100 UG
A metabolite of linoleic acid and an activator of TRPV1; selectively increases calcium levels in HEK293 cells expressing TRPV1 over those expressing TRPV2, TRPV3, TRPV4, and TRPM8 at 100 µM; induces inward currents in HEK293 cells expressing TRPV1; dietary administration reduces weight gain and adipose tissue weight and increases the expression of Ucp1 in wild-type, but not Trpv1 knockout, mice fed a high-fat diet at 0.1% w/w
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