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Medchemexpress LLC 12-HETE-d8 | 2525175-25-9 | 98.0% | 328.52 | 25 UG
Supplier: Medchemexpress LLC 25UGHY113439S
12-HETE-d8 is the deuterium labeled form of 12-HETE, a major metabolic product of arachidonic acid formed via 12-LOX catalysis. It inhibits cell apoptosis in a dose-dependent manner and promotes NF-κB activation and nuclear translocation through the integrin-linked kinase (ILK) pathway. This compound exhibits both anti-thrombotic and pro-thrombotic effects and acts as a neuromodulator.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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