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Medchemexpress LLC 18α-Glycyrrhetinic acid | 1449-05-4 | MFCD00064897 | 470.68 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN0375
18α-Glycyrrhetinic acid is a diet-derived compound that acts as an inhibitor of NF-κB and an activator of proteasome. It serves as a pro-longevity and anti-aggregation factor in multicellular organisms and induces apoptosis.
- Reduces LX-2 cell numbers
- Increases percentage of LX-2 cells in phase G0/G1 and decreases in phase S
- Increases apoptosis in LX-2 cells
- Induces expression of PPAR-γ and alters certain cell cycle and apoptosis-related proteins
- Inhibits NF-κB DNA-binding activity
- Enhances life span of *C. elegans* strains
- Delays paralysis in *C. elegans*
- Reduces Aβ deposits in *C. elegans*
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