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Medchemexpress LLC 1H-pyrido[3,4-b]indole derivative (GNE-149) | 1953132-75-6 | 99.2% | 503.57 | C28H33F4N3O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1453415MG

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GNE-149 is an orally bioavailable full antagonist of estrogen receptor α (ERα) and a selective estrogen receptor degrader (SERD) developed for research into ER-positive breast cancer. It exhibits potent ERα binding and induces receptor degradation, shows low-nanomolar antiproliferative activity in MCF7 and T47D cells, and has demonstrated efficacy in MCF7 xenograft models. Supplied as a solid for laboratory research use.

Catalog No. 50-002-21247


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