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Medchemexpress LLC (1R,3S)-Compound E | 504428-17-5 | 99.6% | C27H24F2N4O3 | 25 MG
Supplier: Medchemexpress LLC 25MGHY14176A
(1R,3S)-Compound E is an isomer of Compound E (HY-14176) and serves as an experimental control. This compound functions as a γ-secretase inhibitor, effectively blocking the cleavage of β-amyloid (40), β-amyloid (42), and Notch γ-secretase, with IC50 values of 0.24, 0.37, and 0.32 nM respectively.
- Isomer of compound E
- Functions as an experimental control
- Acts as a gamma-secretase inhibitor
- Blocks beta-amyloid (40) cleavage
- Blocks beta-amyloid (42) cleavage
- Blocks notch gamma-secretase cleavage
- IC50 values for cleavage are 0.24, 0.37, and 0.32 nM
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