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Medchemexpress LLC (1R,4R)-5-(2-((R)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-6-(6-(4-methoxypyridin-3-yl)-4- | 2769715-68-4 | 99.3% | 592.69 g/mol | C32H36N10O2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY16127510MG

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BI-4732 is an orally active, reversible, ATP-competitive EGFR inhibitor with blood-brain barrier penetration that selectively targets common mutant EGFR variants and has demonstrated intracranial antitumor efficacy in preclinical models.

  • Orally active, reversible EGFR inhibitor with blood-brain barrier penetration.
  • Selective inhibition of mutant EGFR variants including L858R, T790M, and C797S.
  • Demonstrated intracranial antitumor efficacy in xenograft models.
  • High purity (99.3%) suitable for preclinical research.
  • Solid form; soluble in DMSO at approximately 2 mg/mL with warming and sonication.
  • Recommended storage: 4°C protected from light; in solution, store at -80°C (6 months) or -20°C (1 month).

Catalog No. 50-002-88635


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