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Medchemexpress LLC 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-triazolo[1,5-a]pyrimidin-7-amine | 1282041-94-4 | MFCD28502125 | 415.33 g/mol | C14H12F7N5S | 250 MG
SDP

Supplier:  Medchemexpress LLC HY100184250MG

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DSM265 is a triazolopyrimidine-based research compound that potently inhibits Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH). It exhibits biochemical potency (IC50 8.9 nM) and cellular activity against P. falciparum 3D7 parasites (EC50 4.3 nM), and is used in antimalarial mechanism-of-action and biochemical studies.

  • Potent PfDHODH inhibition with an IC50 of 8.9 nM.
  • Inhibits P. falciparum 3D7 parasite growth (EC50 4.3 nM).
  • Selective for parasite DHODH versus human DHODH.
  • Suitable for biochemical and cellular antimalarial assays.

Catalog No. 50-002-15516


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