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Medchemexpress LLC 2(1H)-Pyrimidinone, 4-[2-(3-bromophenyl)ethenyl]-6-(trifluoromethyl)- | 357158-20-4 | C13H8BrF3N2O | 10 MM / 1 ML

Supplier: Medchemexpress LLC HY15368610MM/1ML
BVFP binds to the PGRN588-593 peptide with a Kd of 20 μM. It can disrupt PGRN-SORT1 binding and inhibits SORT1-mediated rPGRN endocytosis.
- Binds to the PGRN588-593 peptide with a Kd of 20 μM.
- Disrupts PGRN-SORT1 binding.
- Inhibits SORT1-mediated rPGRN endocytosis.
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