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Medchemexpress LLC 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine | 293762-45-5 | 99.1% | 340.38 g/mol | C20H16N6 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY10324125MG

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Ro 90-7501 is a small-molecule research compound that inhibits amyloid β42 (Aβ42) fibril assembly and reduces Aβ42-induced cytotoxicity. It has reported activity affecting DNA damage response and phosphatase regulation, and has been used in studies of radiosensitization and antiviral innate immune modulation.

  • Inhibits amyloid β42 fibril assembly and reduces Aβ42-induced cytotoxicity (EC50 ≈ 2 μM).
  • Reported to inhibit ATM phosphorylation and impair DNA repair.
  • Modulates innate immune signaling and inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner.
  • Used in neurodegeneration, amyloid aggregation, and radiosensitization research applications.
  • Molecular formula C20H16N6 and molecular weight 340.38 g/mol.
  • Purity typically reported ≈99.1% and soluble in DMSO.

Catalog No. 50-002-46299


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