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Medchemexpress LLC 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid | 1152782-19-8 | 99.7% | 392.37 g·mol⁻¹ | C20H19F3N2O3 | 10 MG
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Supplier:  Medchemexpress LLC HY10763310MG

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A 1120 (CAS 1152782-19-8) is a high-affinity, nonretinoid antagonist of retinol-binding protein 4 (RBP4) used in preclinical research to modulate the visual cycle and reduce retinal lipofuscin accumulation. It disrupts RBP4 binding to transthyretin, lowers circulating RBP4 and visual-cycle retinoids in animal studies, and has been characterized in structural and pharmacology literature.

  • High-affinity RBP4 antagonist with reported Ki ≈ 8.3 nM.
  • Disrupts RBP4-transthyretin interaction in vitro.
  • Reduces serum RBP4 and visual-cycle retinoids in preclinical models.
  • Decreases retinal lipofuscin bisretinoid accumulation in animal studies.
  • High reported purity (~99.7%) suitable for research use.
  • Molecular formula C20H19F3N2O3; molecular weight ~392.4 g·mol⁻¹.

Catalog No. 50-002-41312


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