Medchemexpress LLC 2-[[4-[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]imino]-1,4-dihydro-1-oxo-2-naphthalenyl]thio]-acetic acid | 881487-77-0 | 98.0% | 443.54 g/mol | C22H21NO5S2 | 10MG

Supplier:  Medchemexpress LLC HY12384710MG

KPT-6566 is a selective, covalent inhibitor of the prolyl isomerase PIN1 that binds the enzyme's catalytic site, promotes PIN1 degradation, and induces DNA damage responses and cell death in cancer models. It is supplied as a solid and as DMSO solutions and is intended for biochemical and cell-based research targeting PIN1-dependent pathways.

• Selective, covalent inhibitor of prolyl isomerase PIN1.
• Binds the catalytic site and promotes PIN1 degradation.
• Demonstrated biochemical potency (PIN1 PPIase IC50 ≈ 640 nM; Ki ≈ 625 nM).
• High purity: 98.0%.
• Molecular formula C22H21NO5S2; molecular weight 443.54 g/mol.
• Available as solid (multiple mg sizes) and as 10 mM solutions in DMSO for assays.
• Suitable for biochemical assays and cell-based cancer research.

Catalog No. 50-002-39369