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Medchemexpress LLC 2-(4-(4-((7-(3,5-difluorobenzyl)-pyrrolo[2,3-d]pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)acetamide | 909561-15-5 | 97.0% | C25H25F2N7O | 10MG
SDP

Supplier:  Medchemexpress LLC HY13477210MG

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AS1810722 is an orally active small-molecule inhibitor of STAT6 used in preclinical research to study Th2-mediated signaling and allergic disease models. It potently inhibits STAT6 (IC50 ≈ 1.9 nM), reduces IL-4 production, and has shown activity in both cell-based differentiation assays and animal models of allergic asthma.

  • Potent STAT6 inhibition with low-nanomolar IC50.
  • Inhibits IL-4 production, modulating Th2 responses.
  • Active in in vitro Th2 differentiation assays.
  • Reduces eosinophil infiltration in animal models of allergic asthma.
  • Suitable for both in vitro and in vivo preclinical studies.
  • Stable as a powder with recommended cold-storage conditions.

Catalog No. 50-002-60222


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