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Medchemexpress LLC ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid-d4 | 1190021-70-5 | 98.7% | 2.5 MG

Supplier: Medchemexpress LLC HYB1826S22.5MG
Adefovir-d4 is the deuterium labeled Adefovir, an adenosine monophosphate analog antiviral agent. After intracellular conversion to Adefovir diphosphate, it inhibits HBV DNA polymerase, with an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. It exhibits good antiviral activity against several viruses, including HBV and herpesviruses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes into drug molecules can affect pharmacokinetic and metabolic profiles.
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