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Medchemexpress LLC 2-Aminoadenosine | 2096-10-8 | 99.8% | 282.26 | 10 G
SDP

Supplier:  Medchemexpress LLC HYW01154810G

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2-Aminoadenosine is a modified adenine base and adenosine analog that stabilizes RNA duplexes and enhances template-directed nucleotide condensation reactions. It forms three hydrogen bonds with uracil to increase the melting temperature of hybrid strands, thereby stabilizing uracil-containing RNA duplexes.

  • Increases U incorporation efficiency to 30% and enhances G incorporation efficiency in template-directed non-enzymatic oligonucleotide synthesis when substituted into a poly(CA) template.
  • Maintains high G incorporation efficiency at reduced substrate concentrations.
  • Depletion of U5 snRNP abolishes pre-mRNA splicing activity in HeLa cell nuclear extracts.

Catalog No. 50-004-55143


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