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Enzo Life Sciences 2-Aminoethoxydiphenyl borate (100mg). CAS: 524-95-8
SDP

Supplier:  Enzo Life Sciences ALX400045M100

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Cell permeable modulator of Ins(1,4,5)-P3-induced Ca2+ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca2+ entry (75µM). Alternative name: 2-APB. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (20mg/ml), dimethyl formamide (20mg/ml) or 100% ethanol (5mg/ml); slightly soluble in PBS, pH 7.2 (50μg/ml). Long Term Storage: -20°C.

Catalog No. 50-200-9085


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