Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000235941

Medchemexpress LLC 2-chloro-1-[2-[3-(trifluoromethyl)anilino]phenyl]ethanone | 2378626-29-8 | 99.7% | 313.70 g/mol | C15H11ClF3NO | 10MM 1ML
SDP

Supplier:  Medchemexpress LLC HY12526910MM 1ML

Encompass_Preferred

TED-347 is a potent, irreversible, covalent, allosteric inhibitor of the YAP-TEAD protein-protein interaction that blocks TEAD transcriptional activity and shows reported antitumor effects in preclinical studies. Reported biochemical activity includes an EC50 of 5.9 μM for TEAD4-Yap1 and a Ki of approximately 10.3 μM; the compound covalently modifies Cys-367 in TEAD4.

  • Irreversible covalent inhibitor of YAP-TEAD interaction.
  • Reported EC50 of 5.9 μM (TEAD4-Yap1) and Ki ≈ 10.3 μM.
  • Covalently modifies Cys-367 in TEAD4.
  • Demonstrated antitumor activity in preclinical studies.
  • Available as DMSO solution and as solid powder for formulation.
  • Molecular formula C15H11ClF3NO; molecular weight 313.70 g/mol.
  • High purity suitable for research applications (reported ≥98%).

Catalog No. 50-002-35941


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.