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Medchemexpress LLC 2-cyano-3-[[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide | 304896-28-4 | MFCD01909444 | 99.6% | 434.27 g·mol-1 | C23H13Cl2N3O2 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10057850MG

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AGK2 is a selective small-molecule inhibitor of SIRT2 used in biochemical and cell-based studies to investigate sirtuin-mediated biology. It has micromolar potency against SIRT2 (IC50 = 3.5 μM) and shows weaker activity against SIRT1 and SIRT3, enabling studies that distinguish SIRT2-specific effects.

  • Selective SIRT2 inhibition (IC50 3.5 μM).
  • Limited activity against SIRT1 and SIRT3 at higher concentrations.
  • Cell-permeable small molecule suitable for cellular studies.
  • Well-characterized in biochemical assays and literature reports.
  • Available as a solid for preparation of stock solutions.

Catalog No. 50-002-12235


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