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Medchemexpress LLC 2-Methylcitric acid-d3 | 146764-58-1 | 98.9% | 209.17 | 1 MG
Supplier: Medchemexpress LLC HY113371S1MG
2-Methylcitric acid-d3 is a deuterium-labeled form of 2-Methylcitric acid, an endogenous metabolite in the 2-methylcitric acid cycle. Its accumulation is observed in methylmalonic and propionic acidemias, where it serves as a marker metabolite. It has been shown to inhibit ADP-stimulated and uncoupled respiration in mitochondria that are supported by glutamate. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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