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Medchemexpress LLC 2-Oxazolidinone, 3-[2-[[(1R)-1-[5-(4-fluoro-3-methylphenyl)-2-pyrimidinyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)- | 1429179-08-7 | 98.8% | 436.48 | 1 ML

Supplier: Medchemexpress LLC HY112289B10MM/1ML
(1R)-IDH889 is an isomer of IDH889 and serves as an experimental control. IDH889 is an orally available, brain penetrant, allosteric, and mutant-specific inhibitor of isocitrate dehydrogenase 1 (IDH1).
- Serves as an experimental control
- Demonstrates potent selectivity for IDH1 R132* mutations
- Potently inhibits R-2-hydroxyglutarate (2-HG) production in cells
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