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Medchemexpress LLC 2-Propenamide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl... | 1226549-39-8 | >98.8% | 476.53 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1821310MM/1ML

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EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM for wild-type EGFR kinase and 28 nM for the double mutant EGFR kinase (L858R/T790M). It exhibits antitumor activity.

  • Potent EGFR kinase inhibitor.
  • IC50 of 7 nM for wild-type EGFR.
  • IC50 of 28 nM for double mutant EGFR kinase (L858R/T790M).
  • Exhibits antitumor activity.
  • Antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM.
  • Appears as a solid, off-white to light yellow color.

Catalog No. 50-003-87648


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