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Medchemexpress LLC 2-Pyridineacetamide, N-[(3-fluorophenyl)methyl]-5-[4-(4-morpholinyl)phenyl]- | 897016-26-1 | 99.1% | 405.46 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY111187

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This compound functions as an inhibitor for Src-kinase and tubulin polymerization. It exhibits favorable oral bioavailability and efficiently permeates the blood-brain barrier in mice. The compound also demonstrates anti-tumor capabilities and prompts apoptosis in Glioblastoma (GBM) cells.

  • Inhibits Src-kinase
  • Acts as a tubulin polymerization inhibitor
  • Possesses good oral bioavailability
  • Readily crosses the blood-brain barrier in mice
  • Shows anti-tumor activity
  • Induces apoptosis of Glioblastoma cells
  • Reduces autophosphorylation of Src in cells
  • Promotes cell cycle arrest at the G2/M phase
  • Inhibits the in vitro assembly of tubulin polymers
  • Significantly delays progression of orthotopic brain tumors
  • Produces long-term survival in a murine model
  • Demonstrates appreciable brain penetration when dosed orally

Catalog No. 50-003-46818


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