Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000387306

Medchemexpress LLC 2-((R)-1-((R)-2-(3-((1,1-difluoro-2-(pyridin-2-yl)ethoxy)methyl)phenyl)-2-hydroxyethyl)-2,3-dihydro-1H-inden-2-yl)acetic acid | 870964-67-3 | 99.28% | 374.48 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1761310MM/1ML

Encompass_Preferred

Evocalcet (KHK7580) is an orally active agonist of the calcium sensing receptor (CaSR) that inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. It can be utilized in the research of hyperparathyroidism.

  • Orally active CaSR agonist.
  • Inhibits parathyroid hormone secretion.
  • Potentially useful for hyperparathyroidism research.
  • Dose-dependently increases intracellular calcium with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
  • Shows no significant inhibitory effects on specific activities of cytochrome P450 isozymes.
  • Reduces serum parathyroid hormone and calcium levels in animal models.
  • Increases serum inorganic phosphorus level in animal models.

Catalog No. 50-003-87306


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.