Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC 2267290-96-8 | 99.9% | 626.66 | 10 MG
Supplier: Medchemexpress LLC 10MGHY134850
QC-01-175 is a heterobifunctional molecule engineered to degrade aberrant tau. It effectively reduces the presence of A152T and P301L mutant tau protein, thereby protecting neurons from tau-mediated toxicity and enhancing cell survival. This compound is constructed from a ligand designed for aberrant tau, an NH2-PEG3 linker, and a ligand for E3 ligase Pomalidomide.
- Degrades aberrant tau protein
- Reduces A152T and P301L mutant tau protein levels
- Offers neuroprotection against tau-mediated toxicity
- Enhances cell survival
- High purity (99.94%)
- Solid, light yellow to green yellow appearance
- Demonstrated in vitro activity in reducing pTau-S396 levels
- Alleviates mitochondrial fragmentation and oxidative stress in SH-SY5Y cells
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?