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Medchemexpress LLC (2S)-3-[3-[[3-cyano-4-(difluoromethyl)-6-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]pyridin-2-yl]amino | 3043939-18-7 | 97.8% | 489.58 g/mol | C24H29F2N5O2S | 10 MG
SDP

Supplier:  Medchemexpress LLC HY16199310MG

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BI-9787 is a potent, zwitterionic ketohexokinase (KHK) inhibitor provided for research use. It exhibits low-nanomolar potency against human KHK isoforms, shows good metabolic stability, and has been characterized in preclinical pharmacokinetic studies.

  • Potent KHK inhibitor with reported IC50 values of 12 nM (hKHK-A) and 12.8 nM (hKHK-C).
  • Zwitterionic structure supporting permeability and oral exposure in preclinical models.
  • Demonstrated metabolic stability and favorable pharmacokinetic properties in rat studies.
  • High chemical purity (~97.8%) suitable for research applications.
  • Molecular weight 489.58 g/mol; formula C24H29F2N5O2S.
  • Available in small pack sizes for dosing and in vivo work.

Catalog No. 50-002-88742


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