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Medchemexpress LLC 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol | 677297-51-7 | 99.4% | 346.34 g/mol | C18H14N6O2 | 10 MG

Supplier: Medchemexpress LLC HY1011110MG
TG100-115 is a selective small-molecule inhibitor of PI3Kγ and PI3Kδ with nanomolar potency (IC50 83 nM and 235 nM, respectively). It is used in biochemical, cellular, and in vivo studies to investigate PI3Kγ/δ-mediated signaling, inflammatory responses, and cardioprotective effects.
- Selective inhibition of PI3Kγ and PI3Kδ.
- Nanomolar potency: PI3Kγ 83 nM, PI3Kδ 235 nM.
- Limited activity against PI3Kα and PI3Kβ (>1 μM).
- High purity (99.41%).
- Molecular weight 346.34 g/mol; formula C18H14N6O2.
- Soluble in DMSO (33.33 mg/mL) with warming and pH adjustment.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
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