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Medchemexpress LLC 3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-1,4-dihydropyrimidin-2-one | 36945-98-9 | MFCD01689072 | 99.3% | 311.29 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11062500MG

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Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. It activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM) and is also described as a "super-cooling agent." It attenuates autoimmune neuroinflammation through modulation of the T-cell response.

  • Super-agonist of the TRPM8 ion channel
  • Activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM)
  • "Super-cooling agent"
  • Attenuates autoimmune neuroinflammation through modulation of the T-cell response

Catalog No. 50-003-43344


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